| Date | Home | Away | Result |
|---|---|---|---|
| 10/24/25 1:30 PM | Modena FC | FC Empoli | 2-1 |
| 10/25/25 8:00 AM | Sampdoria Genua | Frosinone Calcio | 1-1 |
| 10/25/25 8:00 AM | FC Südtirol | FC Cesena | 0-1 |
| 10/25/25 8:00 AM | AC Monza | AC Reggiana 1919 | 3-1 |
| 10/25/25 8:00 AM | US Avellino | Spezia Calcio | 0-4 |
| 10/25/25 8:00 AM | Virtus Entella | Pescara Calcio | 1-1 |
| 10/25/25 10:15 AM | Carrarese Calcio 1908 | FC Venice | 3-2 |
| 10/25/25 12:30 PM | US Catanzaro 1929 | Palermo FC | 1-0 |
| 10/26/25 9:00 AM | Padova Calcio | Juve Stabia | 2-2 |
| 10/26/25 11:15 AM | SSC Bari | Mantova 1911 | 1-0 |